FMCBiopolymer


ALGINATES and ALGINIC ACIDS USP/NF, EP, JP

 

Alginates are natural hydrocolloids of vegetable origin that occur as a structural component in marine brown algae, where they give strength and flexibility to the plant. In contrast to most other polysaccharide gels, alginate gels can develop instantaneously in the presence of divalent cations into acid gels at low pH and constant temperature. The gelling gives rise to a three dimensional network which determines the gel strength. Alginates with high content of G-blocks give stronger gels & M-rich alginates give softer and more fragile gels. The molecular weight determines the viscosity of alginate solutions while the ratio of mannuronic acid guluronic acid (M/G) determines the relative strength of the gel.

FMC range of alginates and alginic acids offer unique gel-forming, film-forming, thickening and stabilizing properties.

Grade Description
 Application
Alginate Type Viscosity (mPas)

Protacid F 120 NM

Alginic Acid

 -

Used in anti‐reflux and effervescent tablets. Also as a natural disintegrant in wet and direct compression granulation.
Kelacid Alginic Acid -
Alginic Acid DC Alginic Acid,
Directly Compressible		 -
Protanal LFR 5/60 Sodium 300 – 700 (10%) Anti‐Reflux Suspensions (Raft formation).
Protanal LF Mg 5/60* Magnesium 1000 - 1800 (7.5%)
Manugel LBA Sodium 300-700 (10%)
Manugel LBB Sodium 8000 (10%)
Protanal LF 240 D Sodium 70 – 200 (1%) Controlled release.
Protanal LF 120 M Sodium 70 – 150 (1%)
Keltone LVCR Sodium 35 (1%)
Keltone HVCR Sodium 400 (1%)
Manucol LKX Sodium 60-170 (1%)
Kelcosol Sodium 1000-1500 (1%) Gelling.
Manugel LBA Sodium 500 (10%)
Manucol LB Sodium 4 (1%) Viscosity enhancer.
Kelcoloid S Propylene Glycol 25 (1%)
Manucol DH Sodium 40-90 (5%) Thickener and stabilizer for syrups, emulsions.
Manucol DMF Sodium 300 (1%)
Kelvis * Sodium 760 (1%)
Protanal Ester SD-LB Propylene Glycol 700 - 1800 (2%)
Kelcoloid K3B426 Propylene Glycol 120 (1%)
Kelcoloid HVF * Propylene Glycol 400 (1%)
Kelcoloid LVF * Propylene Glycol 120 (1%)
Manucol Ester E/RK * Propylene Glycol 125 (1%)
Manucol Ester M * Propylene Glycol 200 (1%)
Protanal KF 200 * Potassium 200 – 400 (1%) Dental Impression materials.
Protanal TA 250 * Triethanolamine 200 – 400 (1%)
Kelmar * Potassium 400 (1%)
Manucol SS / LL Sodium 200 (1%) Dental Fixtures.
Kelset Sodium-Calcium 500 –1000 (0.5%) Self‐gelling polymers for controlled release.
Keltose * Ammonium-Calcium Semi-gel (1%)
Protanal LF 200 M Sodium 200 – 400 (1%) Wound Healing.
Protanal LF 10/60Sodium20 - 70 (1%)
Manucol LF Sodium 25 (1%)
* Non-pharmacopeial grades