|

KOLLIDON
Povidone USP/NF, EP, JP The soluble grades of Kollidon are polyvinylpyrrolidone (PVP K) obtained by free-radical polymerization of N-vinylpyrrolidone. By virtue of its solubility in water and many organic solvents as well as its high binding power and ability to form complexes, soluble PVP occupies a special position among the synthetic colloids. Soluble Kollidon is available in a variety of grades based on their K-value and weight average molecular weight.
| Grade | Description
| Applications
| | K‐value | Weight average molecular weight (Mw) | Kollidon 12 PF | 10.2 - 13.8 | 2000-3000 | Low molecular weight povidone of pyrogen-free quality for use as a solubilizer, crystallization inhibitor and suspension stabilizer in injections. | | Kollidon 17 PF | 15.3 - 18.0 | 7000-11000 | Same as Kollidon 12 PF. Additionally used as a lyophilization agent in injections and ophthalmic preparations. | | Kollidon 25 | 22.5 - 27.0 | 28000 - 34000 | Medium molecular weight povidone used as binders in tablets, capsules and granules, stabilizers in oral suspensions, as film formers, oral solubilizers, dispersants for pigments, enzyme stabilizers and as bioavailability enhancers | | Kollidon 30 | 27.0 - 32.4 | 44000 - 54000 | | Kollidon 30 LP | 27.0 - 32.4 | 44000 - 54000 | Special low-peroxide and low- formaldehyde grade to prevent degradation of actives sensitive to oxidation. Other applications similar to Kollidon 30 | | Kollidon 90 F | 81.0 - 96.3 | 1000000 - 1500000 | High molecular weight povidone serving as a highly effective binder, stabilizer for oral and topical solutions, thickener, hydrophilizer and pore-former in surgical plastics. |
|