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LUTROL® E
Polyethylene Glycol (Macrogol) USP/NF, EP Lutrol E types are liquid polyethylene glycols manufactured by alkali-catalysed polymerisation of ethylene oxide with subsequent neutralisation of the catalyst. Lutrol E grades are readily soluble in water, ethanol, acetone, glycols and chloroform. The number in the name of the product is indicative of the average molecular weight. The higher the molecular weight of the product; the less hygroscopic it is and lower it’s solubility in water.
Lutrol E 300 and Lutrol E 400 are colourless, almost odourless and tasteless liquids at room temperature; while Lutrol E 600 can be either liquid or pasty at room temperature.
| Grade | Description
| Application
| Lutrol E 300 | Molecular weight : 285 - 315 Viscosity : 5.4 - 6.4 mPa.s | Used as solvents and solubilizing agents for oral, parenteral, topical, ophthalmic and rectal preparations. Carriers for dissolved or suspended drug in soft gelatin capsules. Widely used as an ointment base. | | Lutrol E 400 | Molecular weight : 380 - 420 Viscosity : 6.8 - 8.0 mPa.s | | Lutrol E 600 | Molecular weight : 570 - 630 Viscosity : 9.9 – 11.3 mPa.s |
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