Gum base is a non-nutritive, non-digestible, water-insoluble masticatory delivery system designed to carry sweeteners, flavours, minerals, vitamins, active pharmaceutical ingredients and other desired substances in chewing gum. The composition of gum bases differ but generally consist of elastomers, resins, waxes, fats, emulsifiers, fillers and anti-oxidants in varying proportions.

This new, alternative drug delivery system may contain one or more active substances, which are released on chewing, subsequent to which the gum base should be discarded and not swallowed. Gum base products provide fast onset of action with high bioavailability and pleasant taste. They can be taken anywhere, at any time without the requirement of water, promoting high patient compliance.