Shin-Etsu AQOAT® (HPMCAS)
 
Hydroxypropyl Methylcellulose Acetate Succinate USP/NF, JP

Aqoat is a new enteric coating material for application in an aqueous, solvent and dry coating system. A suspension of Aqoat, triethyl citrate and water is applied for coating. Can also be used in the design of sustained release dosage form in combination with gastric soluble preparation.

 
 
 
GRADE
DESCRIPTION
APPLICATION
DISSOLVING pH*
ACETYLl(%) / SUCCINOYL(%)
> 5.5
8 /15
Micronized grade for aqueous & dry coating
> 6.0
9 /11
> 6.5
12 /6
> 5.5
8 /15
Granular grade for solvent-based coating
> 6.0
9 /11
> 6.5
12 /6
* Mcllvaine's buffer (citric acid-Na2HPO4)

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