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BLANOSE®
CELLULOSE GUM  |
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| Sodium
Carboxymethylcellulose USP/NF, EP, JP Blanose
cellulose gum is the sodium salt of carboxymethylcellulose
(CMC), purified to meet pharmaceutical standards. They are
soluble in water but insoluble in organic solvents. Generally
used as thickeners, binders, stabilizers, suspending agents
and rheology modifiers. Lower substitution types provide thixotropy
and higher substitution types are used where smooth solutions
are required.
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| GRADE |
TYPICAL
2% VISCOSITY |
APPLICATIONS |
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2500
- 4500 (1%) |
Tablet
coatings - Film former
Mucoadhesives
- Absorbency
Syrups
& suspensions - Thickener ,suspending agent
Sustained
release - Thickener, diffusion barrier
Bulk
laxatives - Physiologically inert, high water binding capacity
Ointments,
creams and lotions - Stabilizer, thickener, film-former
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1000
- 2800 (1%) |
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1000
- 2800 (1%) |
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1500
- 2500 (1%) |
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1500
- 3100 (2%) |
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200 - 800 (2%) |
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400 - 600 (2%) |
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50 - 100 (2%) |
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25 - 50 (2%) |
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2500
- 4500 (1%) |
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1500
- 3100 (2%) |
Blanose 9M8F-PH |
400 - 800 (2%) |
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200 - 800 (2%) |
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1500
- 3500 (2%) |
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*
Concentration in water, weight%. Viscosities determined at 25 degree
C, using a Brookfield LVF viscometer |
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| D-S TYPE |
SUBSTITUTION
RANGE |
SODIUM CONTENT
% |
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7 |
0,65 to 0,90 ** |
7,0
- 8,9
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| 9 |
0,80
to 0,95 |
9,2
- 9,3 |
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12 (For USP Grades) |
1,15
to 1,45 |
10,4
- 12,0 |
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12 (For EP Grades) |
1,12
to 1,21 |
10,2
- 10,8 |
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i**
in 7S and 7O types, the upper limit of substitution is 0,95. |
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