NATROSOL® 250 PHARM
 
Hydroxy Ethyl Cellulose USP/NF, EP

Natrosol HEC is a non-ionic water-soluble cellulose ether, formed by reaction of cellulose with ethylene oxide. It is used as a modified release tablet matrix, a film former and a thickener, stabilizer and suspending agent for oral and topical applications when a non-ionic material is desired. Natrosol is easily dispersed in cold or hot water to give solutions of varying viscosities and desired properties, yet it is insoluble in organic solvents.

 
GRADE
VISCOSITY RANGE (cps)*
APPLICATION
3500 - 5500 (at 1%)

Modified release - provides effective diffusion limiting matrix systems.

Tablet coating - Imparts flexibility to films while providing a good barrier to water and oxygen transmission

Solution thickening, stabilizing and suspending agent - Controls rheology and provides pseudoplasticity

1500 - 2500 (at 1%)
4500 - 6500 (at 2%)
250 - 400 (at 2%)
Natrosol L Pharm
75 - 150 (at 5%)
* Concentration in water, weight%. Viscosities determined at 25 degree C, using a Brookfield LVF viscometer

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